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Lecture Schedule - 2009

Mondays 1-3 KN137


Note: Students are required to read the specific on-line lecture material before coming to lecture. In lecture I will not review all of the details covered in that online material but instead will focus on the important concepts and their relevance. In tutorials, we will cover topics that complement the lecture content.

Request to Adjust Grading Scheme for Missed Tests

Part I. Cell Adhesion, Communication and Signal Transduction
Sept. 14 1. Introduction to Human Cell Biology
Sept. 14 2. The Human Cell Membrane
Sept. 21 3. Junctional Adhesion Complexes: Skin, Guts, Heart & Sperm
Sept. 21 4. Gap Junctions and Communication in the Heart and Glands
Sept. 28 5. Adhesion Molecule Types & Functions
Sept. 28 6. Signal Transduction & Erectile Dysfunction
Oct. 5 7. Insulin and Sugar Mobilization: cAMP Signaling from Receptor to Function
Oct. 5 8. Muscarinic Receptors: This Lecture Ends in Tears
Oct. 12   Thanksgiving: No Class
Oct. 19. 9. Signal Transduction and Alzheimer’s Disease: Calcium & Calmodulin
Part II. The Cytoskeleton, Intracellular Trafficking & Disease
Oct. 19 10. Motoring along on Microtubules
Oct. 26   1st Midterm Test (2 hours; lecture room) — Makeup test 8AM, Sat. Nov. 14
Nov. 2 11. Allergens and Myosins; Actin & Infection
Nov. 2 12. Leukocytes, WASPs and ROCK & Rho
Nov. 9 13. Influenza Virus and HIV Entry
Nov. 9 14. Lysosomes: Death by Enzyme Malfunction
Nov. 16 15. Tay Sachs: A Protein Targetting Disease
Nov. 16 16. COPs, SNARES, Rabs & Huntington’s Disease
Nov. 23 17. Cell Biology of Cancer
Nov. 23 18. Epidermal Growth Factor Signal Transduction and Breast Cancer
Nov. 23 19. EGF-Like Peptide Function in Dictyostelium discoideum
Nov. 30 20. Nucleocytoplasmic Transfer
Nov. 30 21. Nuclear and Nucleolar Localization Sequences
Final Exam (3 hours; during final exam period)


Textbook: No Textbook is required because there are none available on human cell biology or that cover the subject matter in the way this course does; any recent Cell & Molecular textbook will suffice; students are also encouraged to use the library resources to check for recent review articles on topics covered in the course.

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University of Toronto at Mississauga